They both calm your immune system’s reaction to allergens. They also take effect at different times and stay effective for different durations. Antihistamines have a reputation of making you sleepy because the first types crossed into your central nervous system more easily and had a direct effect on your alertness.These factors could determine which of these two drugs is better for you. However, newer antihistamines like Zyrtec and Claritin are less likely to cause this side effect. Most people experience at least 24 hours of relief after a single dose. People who take it may feel relief in as little as one hour.
All are efficacious in controlling symptoms of allergic rhinitis (ie, sneezing, rhinorrhea, itching) but do not significantly improve nasal congestion.
Research into aspects of pharmacokinetics and efficacy and adverse effect profiles of bilastine in children under 12 years of age is needed as are dose-response assessments and studies planned rigorously with the aim of assessing quality of life effects.
Current guidelines for diagnosis and treatment of allergic rhinoconjunctivitis and urticaria recommend nonsedating antihistamines as first line treatment [1, 2].
Among the most popular over-the-counter (OTC) allergy meds are Zyrtec and Claritin.
These two allergy drugs produce very similar results. Both cetirizine and loratadine are nonsedating antihistamines.