[ Read the disclaimer | Adults: Allergic rhinitis, seasonal/perennial: 5 mg po qd. In patients with liver or renal impairment, a starting dose of one 5 mg tablet every other day is recommended based on pharmacokinetic data.
Mechanism of Action Desloratadine is a long-acting tricyclic histamine antagonist with selective H1-receptor histamine antagonist activity.
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The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgment. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.The list is ordered alphabetically according to the condition or conditions, then by the generic name of each medication.The list is not exhaustive and not all drugs are used regularly in all countries.Receptor binding data indicate that at a concentration of 2–3 ng/m L (7 nanomolar), desloratadine shows significant interaction with the human histamine H1-receptor.Desloratadine inhibited histamine release from human mast cells in vitro.